There are a number of things you can do before your plane leaves to ensure a smooth and comfortable journey:

At Check-In

• If you're prone to motion sickness, consider asking for a seat over a wing or the wheels, which are the steadiest parts of an aircraft.
• Depending on your preference for more space or better view, you may want to book a window or aisle. Window seats are good idea if you want to sleep during the flight, as they offer you a wall to rest against, and prevents your neighbor from disturbing you when they leave their seats during the flight.
• Ask to sit in an emergency aisle or bulkhead seat for extra legroom. However, you should be aware that although bulkhead seats often offer more legroom (some in fact offer less), you may not be able to see the in-flight movie. Your seat tray (and in some cases, movie screen) will usually be situated in your armrest, which may mean that your seat is slightly narrower. The bulkhead is also the place where families with young babies are seated.
• Avoid the seats in front of an emergency aisle or bulkhead, as they generally don't recline.
• Make sure that the agent checking your bags attaches a destination tag to each one. Check to see that these tags show the three-letter code for your destination airport. Make sure that you have removed any tags from previous trips to avoid confusion.

After Check-In

• Keep an eye on the flight information monitors to ensure that you arrive at you gate in plenty of time.
• Avoid heavy meals and alcohol.
• Take a walk around the terminal to minimize stress and to reduce the risk of DVT.
• Apply a good moisturiser to keep skin feeling fresh.